Pharmacists

All patient handouts are located here.

Renal Pharmacist Performance Expectations (pdf download)

Vancomycin Predialysis Concentrations

Aminoglycoside Protocol 3x per week HD

Cefazolin Short DailyHD Modeling

Meropenem 3x per week HD Modelling

Stepwise Approach to Uremic Pruritus *New*

Appendix: Hydroxyzine (Atarax®) and Risk of QT Interval Prolongation and Torsades de Pointes *New*

 

Compatibility of Common Drugs With Peritoneal Dialysis Solutions

(Prepare immediately prior to use)
DRUG PD SOLUTION
DIANEAL EXTRANEAL NUTRINEAL PHYSIONEAL
Calcium gluconate Yes Unknown Unknown Unknown
Cefazolin Yes Yes Unknown Yes
Cefazolin+ Ceftazidime Yes Unknown Unknown Unknown
Cefazolin+ Gentamicin Yes Unknown Unknown Unknown
Cefazolin+ Gentamicin+ Heparin Yes Unknown Unknown Unknown
Cefazolin+ Heparin Yes Unknown Unknown Unknown
Cefazolin+ Insulin Yes* Unknown Unknown Unknown
Cefazolin+ Heparin+ Insulin Yes* Unknown Unknown Unknown
Cefazolin+ Tobramycin Yes* Unknown Unknown Unknown
Ceftazidime Yes Yes Unknown Unknown
Ceftazidime+ Heparin Yes Unknown Unknown Unknown
Ceftazidime+ Tobramycin Yes Unknown Unknown Unknown
Ceftazidime+ Vancomycin Yes Unknown Unknown Unknown
Ceftazidime+ Vancomycin+ Heparin Yes Unknown Unknown Unknown
Erythromycin Yes Unknown Unknown Unknown
Fluconazole Yes Unknown Unknown Unknown
Gentamicin Yes Yes Yes Yes
Gentamicin+ Heparin Yes Unknown Unknown Unknown
Gentamicin+ Insulin Yes* Yes Unknown Unknown
Gentamicin+ Heparin+ Insulin Yes* Unknown Unknown Unknown
Gentamicin+ Vancomycin Yes Yes Unknown Unknown
Gentamicin+ Vancomycin+ Insulin Unknown Yes Unknown Unknown
Heparin Yes Yes Yes Yes
Heparin+ Insulin Yes* Yes Yes Unknown
Insulin Yes Yes Yes Yes
Metoclopramide Yes Unknown Unknown Unknown
Potassium chloride Yes Yes up to4 meq/L Unknown Unknown
Sodium bicarbonate Yes Unknown Unknown In product
Tobramycin Yes Unknown Unknown Yes
Tobramycin+ Heparin Yes Unknown Unknown Unknown
Tobramycin+ Insulin Yes* Unknown Unknown Unknown
Tobramycin+ Heparin+ Insulin Yes* Unknown Unknown Unknown
Tobramycin+ Vancomycin Yes Unknown Unknown Unknown
Vancomycin Yes Yes Yes Yes
Vancomycin+ Heparin Yes Yes Unknown Unknown
Vancomycin+ Insulin Yes* Yes Unknown Unknown
Vancomycin+ Heparin+ Insulin Yes* Yes Unknown Unknown

*Data on compatibility is based on current practice.

Version 1 – Pharmacy Document
Department of Pharmacy, SBGH
May, 2005

References

Bailie GR, Kane MP. Stability of drug additives to peritoneal dialysate. Perit Dial Int 1995; 15:328-35.
Baxter Physioneal Monograph.
Baxter Study Tables, faxed May 28, 2003.
Benz RL, Schleifer CR, et al. Successful treatment of postparathyroidectomy hypocalcemia using continuous ambulatory intraperitoneal calcium (CAIC) therapy. Perit Dial Int 1989; 9:285-8.
Dahl NV, Foote EF, et al. Pharmacokinetics of intraperitoneal fluconazole during continuous cycling peritoneal dialysis. Ann Pharmacother 1998; 32:1284-9
Dorval M, Legault L, et al. Practical aspects of the addition of sodium bicarbonate to peritoneal dialysate. Perit Dial Int 2000; 20(6):791-3.
Keane WF, Bailie GR, et al. Adult peritoneal dialysis-related peritonitis treatment recommendations: 2000 update. Perit Dial Int 2000; 20(4): 396-411.
Nephrology Pharmacy Associates. Peritoneal Dialysis 2004 – A Guide to Medication Use.
Sewell DL, Golper TA, et al. Stability of single and combination antimicrobial agents in various peritoneal dialysates in the presence of insulin and heparin. Am J Kidney Dis 1983; 3:209-12.

The following links are listed in alphabetical order. The MRP is not resposible for the content contained within the links provided.

2011 Dialysis of Drugs (Genzyme)
The Iron Deficiency Anemia Newsletter
Cockcroft and Gault
CSHP Manitoba Branch
Dalhousie Pharmacy Drug Information Resources for Renal Pharmacists
DPIN Login
Epoetin alfa product monograph
2010 FNIHB Provider Guide for Pharmacy Benefits
Ferrlecit Product monograph
Health Canada Drug Product Database
HDCN
KDOQI
Manitoba Pharmacare
Medscape Nephrology
MDRD Equation
Micromedex
Natural Medicines comprehensive database
Renal Pharmacists
WRHA Pharmacy Insite