IgA Nephropathy

IgA Nephropathy

IgA (Immunoglobulin A) = The IgA protein, an antibody, is a normal part of the body’s immune system (the system that protects against disease).

Nephro = Kidney

Pathy = Disease

IgA nephropathy is a disease caused by the reaction of the kidneys to IgA proteins. Over a period of many years the filters become blocked and the kidneys may fail.

Who is at risk?

  • Unknown
  • A small percent of patients have a family or inherited risk (genetic factors)

How is IgA Nephropathy diagnosed?

  • Urine test to look for blood in the urine

How are the kidneys affected?

  • Over time 25 percent of kidney patients will progress where the filters become damaged and the kidneys may fail

What are the signs and symptoms of IgA Nephropathy?

  • Foamy urine (caused by protein leaking from the tiny filters)
  • Bloody, tea colored or cloudy urine
  • Swelling around the eyes, hands or feet
  • High blood pressure

How is IgA treated?

  • Mild cases may recover with or without treatment
  • Good blood pressure control: Healthy eating, Regular physical activity
  • Medications
  • May use fish oil supplement
  • If your kidney disease declines to end stage kidney disease you will need: Dialysis treatments, Kidney transplant, No treatment/End of Life Care

References: Mayo Clinic